HAL® Therapy – current scientific studies

This list of the studies is updated on regular basis. All published studies will be listed here as soon as possible.

Last updated: 02. February 2015

Chihara H., Takagi Y., Nishino K. et al

Factors Predicting the Effects of Hybrid Assistive Limb Robot Suit during the Acute Phase of Central Nervous System Injury.

Neurol Med Chir (Tokyo). 2016 Jan 15;56(1):33-7. doi: 10.2176/nmc.oa.2015-0178. Epub 2015 Nov 5.

Keywords: robot suit; HAL; rehabilitation

Ogata T., Abe H., Samura K. et al

Hybrid Assistive Limb (HAL) Rehabilitation in Patients with Acute Hemorrhagic Stroke.

Neurol Med Chir (Tokyo). 2015 Dec 15;55(12):901-6. doi: 10.2176/nmc.oa.2015-0209. Epub 2015 Oct 28.

Keywords: acute stroke; intracerebral hemorrhage; hybrid assistive limb; rehabilitation; outcome; functional independence measure

Fukuda H., Morishita T., Ogata T. et al

Tailor-made Rehabilitation Approach Using Multiple Types of Hybrid Assistive Limb Robots for Acute Stroke Patients: A Pilot Study.

Assist Technol. 2015 Oct 19. [Epub ahead of print]

Keywords: hybrid assistive limb; neurorehabilitation; physical impairment; robot; stroke rehabilitation

Sczesny-Kaiser M., Höffken O., Aach M. et al

HAL® exoskeleton training improves walking parameters and normalizes cortical excitability in primary somatosensory cortex in spinal cord injury patients

J Neuroeng Rehabil. 2015 Aug 20;12:68. DOI: 10.1186/s12984-015-0058-9.

Yoshimoto T., Shimizu I., Hiroi Y. et al

Feasibility and efficacy of high-speed gait training with a voluntary driven exoskeleton robot for gait and balance dysfunction in patients with chronic stroke: nonrandomized pilot study with concurrent control.

Int J Rehabil Res. 2015 Aug 18. [Epub ahead of print]

Fukuda H., Samura K., Hamada O. et al

Effectiveness of Acute Phase Hybrid Assistive Limb Rehabilitation in Stroke Patients Classified by Paralysis Severity.

Neurol Med Chir (Tokyo). 2015;55(6):487-92. DOI: 10.2176/nmc.oa.2014-0431. Epub 2015 Jun 2.

Aach M., Meindl R.C., Geßmann J. et al

Exoskelette in der Rehabilitation Querschnittgelähmter – Möglichkeiten und Grenzen

Unfallchirurg. 2015 Feb;118(2):130-7. DOI: 10.1007/s00113-014-2616-1.

Keywords: Locomotion; Gait support; Application area; Remaining motor functions; Neuropathic pain

Aach M., Cruciger O., Sczesny-Kaiser M. et. al

Voluntary driven exoskeleton as a new tool for rehabilitation in chronic spinal cord injury: a pilot study

Spine J. 2014 Dec 1;14(12):2847-53. DOI: 10.1016/j.spinee.2014.03.042.

Keywords: Exoskeleton; Hybrid assistive limb; Paraplegia; Rehabilitation; Spinal cord injury; Treadmill training

Cruciger O., Schildhauer T.A., Meindl R.C. et al

Impact of locomotion training with a neurologic controlled hybrid assistive limb (HAL) exoskeleton on neuropathic pain and health related quality of life (HRQoL) in chronic SCI: a case study

Disabil Rehabil Assist Technol. 2014 Nov 10:1-6. DOI: 10.3109/17483107.2014.981875.

Keywords: Chronic neuropathic pain; exoskeleton; health related quality of life; locomotion training; spinal cord injury

Watanabe H., Tanaka N., Inuta T. et al

Locomotion improvement using a hybrid assistive limb in recovery phase stroke patients: a randomized controlled pilot study.

Arch Phys Med Rehabil. 2014 Nov;95(11):2006-12. doi: 10.1016/j.apmr.2014.07.002. Epub 2014 Jul 7.

Keywords: Gait; Locomotion; Rehabilitation; Robotics; Stroke

Cruciger O., M. Tegenthoff M., Schwenkreis P. et. al

Locomotion training using voluntary driven exoskeleton (HAL) in acute incomplete SCI

Neurology. 2014 Jul 29;83(5):474. DOI: 10.1212/WNL.0000000000000645.

Nilsson, K. Skough Vreede, V. Häglund et al

Gait training early after stroke with a new exoskeleton – the hybrid assistive limb: a study of safety and feasibility

J Neuroeng Rehabil. 2014 Jun 2;11:92. DOI: 10.1186/1743-0003-11-92.

Keywords: Gait; Stroke; Rehabilitation; Robotics

Kawamoto H., Kamibayashi K., Nakata Y. et al

Pilot study of locomotion improvement using hybrid assistive limb in chronic stroke patients.

BMC Neurol. 2013 Oct 7;13:141. doi: 10.1186/1471-2377-13-141.

Kubota S., Nakata Y., Eguchi K. et al

Feasibility of rehabilitation training with a newly developed wearable robot for patients with limited mobility

Arch Phys Med Rehabil. 2013 Jun;94(6):1080-7. DOI: 10.1016/j.apmr.2012.12.020.

Keywords: Feasibility studies; Mobility limitation; Orthopedic equipment; Rehabilitation; Robotics

Sczesny-Kaiser M., S. Lissek S., Höffken O. et al

Exoskelettales Rehabilitationstraining bei Querschnittgelähmten – Fallserie zur neuronalen Plastizität.

Trauma Berufskrankh 2013 – 16:1974. DOI: 10.1007/s10039-013-1974-1.

Keywords: Spinal cord injuries; Paraplegia; Somatosensory cortex; Magnetic resonance imaging, functional; Cortical plasticity

Aach M., Sczesny-Kaiser M., Lissek S. et al

Exoskelettales Rehabilitationstraining bei Querschnittgelähmten. Fallserie zum funktionellen Outcome.

Trauma Berufskrankh 2013 – 16:1977. DOI: 10.1007/s10039-013-1977-y.

Keywords: Exoskeletal rehabilitation; Paraplegia; Spinal cord injuries; Locomotion; Walking capacity

Pons J.L. et al. (Eds.)

Exoskeletal Neuro-Rehabilitation in Chronic Paraplegic Patients – Initial Results

Converging Clinical & Engi. Research on NR 2013, BIOSYSROB 1, pp.233 – 236.